Zamboanga Sibugay covers a total area of 3,607.75 square kilometres (1,392.96 sq mi) occupying the south-central section of the Zamboanga Peninsula in western Mindanao, at 7°48’N 122°40’E. To the north it intersects the common municipal boundaries of Kalawit, Tampilisan, and Godod of Zamboanga del Norte. It is bordered to the west by the municipalities of Sirawai, Siocon, and Baliguian, to the south by the Sibuguey Bay, and to the east by the municipalities of Bayog and Kumalarang of Zamboanga del Sur. It is further bordered on the southwest by Zamboanga City.
The leading industries are in the areas of semi-processed rubber, rice and corn milling, ordinary food processing, wood and rattan furniture making, dried fish and squid processing, and home-made food processing. New industries include concrete products, garments, wax and candle factories, lime making, and other home and cottage industries.
Major crops produced include rice, corn, coconuts, rubber, fruit trees, vegetables, tobacco, coffee, cacao, and root crops. Livestock and poultry productions are predominantly small-scale and backyard operations. Coal mining in large and small scale and precious metal mining in small scale category are likewise present in some areas of the province.